Impact of sub and supra-threshold adaptation currents in networks of spiking neurons

by David Colliaux, Pierre Yger, Kunihiko Kaneko
Abstract:
Neuronal adaptation is the intrinsic capacity of the brain to change, by various mechanisms, its dynamical responses as a function of the context. Such a phenomena, widely observed in vivo and in vitro, is known to be crucial in homeostatic regulation of the activity and gain control. The effects of adaptation have already been studied at the single-cell level, resulting from either voltage or calcium gated channels both activated by the spiking activity and modulating the dynamical responses of the neurons. In this study, by disentangling those effects into a linear (sub-threshold) and a non-linear (supra-threshold) part, we focus on the the functional role of those two distinct components of adaptation onto the neuronal activity at various scales, starting from single-cell responses up to recurrent networks dynamics, and under stationary or non-stationary stimulations. The effects of slow currents on collective dynamics, like modulation of population oscillation and reliability of spike patterns, is quantified for various types of adaptation in sparse recurrent networks.
Reference:
David Colliaux, Pierre Yger, Kunihiko Kaneko, 2015. Impact of sub and supra-threshold adaptation currents in networks of spiking neurons, Journal of computational neuroscience, volume 39.
Bibtex Entry:
@article{Colliaux2015,
 abstract = {Neuronal adaptation is the intrinsic capacity of the brain to change, by various mechanisms, its dynamical responses as a function of the context. Such a phenomena, widely observed in vivo and in vitro, is known to be crucial in homeostatic regulation of the activity and gain control. The effects of adaptation have already been studied at the single-cell level, resulting from either voltage or calcium gated channels both activated by the spiking activity and modulating the dynamical responses of the neurons. In this study, by disentangling those effects into a linear (sub-threshold) and a non-linear (supra-threshold) part, we focus on the the functional role of those two distinct components of adaptation onto the neuronal activity at various scales, starting from single-cell responses up to recurrent networks dynamics, and under stationary or non-stationary stimulations. The effects of slow currents on collective dynamics, like modulation of population oscillation and reliability of spike patterns, is quantified for various types of adaptation in sparse recurrent networks.},
 author = {Colliaux, David
and Yger, Pierre
and Kaneko, Kunihiko},
 day = {24},
 doi = {10.1007/s10827-015-0575-3},
 issn = {1573-6873},
 journal = {Journal of computational neuroscience},
 keyword = {Synapses},
 language = {eng},
 month = {Dec},
 number = {3},
 pages = {255--270},
 title = {Impact of sub and supra-threshold adaptation currents in networks of spiking neurons.},
 url = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649064/pdf/10827_2015_Article_575.pdf},
 volume = {39},
 year = {2015}
}