I am a PhD student working on the impact of the axon initial segment geometry on excitability. I am interested in understanding how the axon initial segment geometry influences the generation of the action potential and its transmission to the soma. To address this question I am using biophysical theory, modelling tools (Brian2) and patch-clamp experiments on cultured neurons with controlled geometry.
- , 2021. Electrical match between initial segment and somatodendritic compartment for action potential backpropagation in retinal ganglion cells, Journal of Neurophysiology.
- , 2020. Theoretical relation between axon initial segment geometry and excitability, eLife, volume 9.
- , 2016. Covariation of axon initial segment location and dendritic tree normalizes the somatic action potential, Proceedings of the National Academy of Sciences of the United States of America, volume 113.